T2 distribution reflects Multiple Sclerosis pathologies: Histology driven regions of interest
نویسندگان
چکیده
Introduction: Multi-echo T2 relaxation allows scientists to probe water micro-compartments in vivo [1]. T2 relaxation is sensitive to myelin content [2] and has uncovered previously undetected micro-compartments in MS and PKU pathological tissue [3]. We aim to characterize how T2 distributions of fixed brain change with different types of MS pathology, identified using ex vivo histological stains, in order to create a model of T2 distributions specific to stages of MS disease.
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